
When in the area of the Pearl Pendant over the filthy water, the P.R.L. will lock onto and destroy most crates, bear traps, dynamite traps, and blue medallions, and destroy them (though the counter which keeps track of the number of blue medallions will not appear on-screen if the medallion was not the primary target).

In Resident Evil 4 HD, which is based on the Wii version of the game, the P.R.L. It also cannot harm Ashley or the Merchant. The weapon was changed for the Wii version, where it charges much faster and fires multiple beams which hit multiple enemies on screen without aiming. 412 cannot damage or affect any inanimate objects, including barrels, chains, switches, etc. In the PlayStation 2 and PC version, the P.R.L. " Use the charge attack to decimate all surrounding enemies with this supremely powerful laser weapon!" However, when fully charged, the full laser sight is shown, making it decent for long-range shots. It can also take down groups as in the Wii version, it has a recoil force, so you basically don't have to aim, though that decreases your overall accuracy. 412 fires a penetrating laser beam that pierces and kills most enemies in one shot. It can also kill some creatures with just the flash, like the Verdugo and even Osmund Saddler.

This flash can destroy most enemies in 3-4 hits. 412 is a short-ranged pulse of light, which damages and stuns enemies, much like a flash grenade. Once fired, the weapon must recharge its basic energy pool, so you can't just blast away with flashes, or continuously charge the main laser. If the meter glows red, release the fire button and you can take down any boss or enemy with ease. This weapon has a meter that shows how charged up the weapon is when you hold the fire button. The weapon has 2 settings, a flash, where you just aim and fire, or a charged blast. The weapon has no listed stats and cannot be upgraded.

It is equivalent in size to the Chicago Typewriter. 412 takes up 21 spaces (7x3) of Leon's inventory, making it one of the bulkiest weapons in the game. Once unlocked, the weapon is free when the player starts a new round on any completed game. It is unlocked by beating the main game on Professional mode. 412 must be unlocked before it can be used.
